Isidore De Rudder had his education at the Academie van Brussel from 1869 to 1880, where his most important teacher the sculptor Eugène Simons was.
In 1880 he made his début in the Salon in Gent with "A Child's Head".
During his entire career he made style objects, portraits and bustes. In 1882 he received the Second Price Of Rome behind Charlier.
He designed façade sculptures and decorative sculpture in silver (at Wolfers), in ivory, porcelain and ceramic.
His bronze figures and bustes executed at Luppens in Brussels were of high quality. Made many funerary monuments and othe public objects.
His work is shown in, among others, musea in Brussels, Antwerp, Brussels Herb Garden, numerous façades, and private collections.